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Image Search Results
Journal: Journal of pharmacological sciences
Article Title: Peripheral administration of interleukin-13 reverses inflammatory macrophage and tactile allodynia in mice with partial sciatic nerve ligation.
doi: 10.1016/j.jphs.2016.11.005
Figure Lengend Snippet: Fig. 1. Upregulation of interleukin-13 receptor a1 (IL-13Ra1) in accumulating macrophages. Mice were subjected to partial sciatic nerve (SCN) ligation (PSL) or sham surgery, and the SCN was collected. The time course of IL-13 (A) and IL-13Ra1 (B) mRNA expression in the injured SCN after PSL was evaluated by RT-qPCR. Data are presented as the mean ± SEM of 5e6 mice. ***P < 0.001 vs sham control. (C) Localization of IL-13Ra1 protein on accumulating F4/80þ macrophages in the injured SCN on day 7 after PSL was visualized by immunohistochemistry. Representative micrographs in longitudinal sections are shown. Scale bars ¼ 20 mm.
Article Snippet: Sections were blocked with 4% bovine serum albumin for 2 h and incubated at 4 C overnight with primary
Techniques: Ligation, Expressing, Quantitative RT-PCR, Control, Immunohistochemistry